2019 Novel Coronavirus (COVID-19) Pneumonia: Serial Computed Tomography Findings.

From December 2019, Coronavirus disease 2019 (COVID-19) pneumonia (formerly known as the 2019 novel Coronavirus [2019-nCoV]) broke out in Wuhan, China. In this study, we present serial CT findings in a 40-year-old female patient with COVID-19 pneumonia who presented with the symptoms of fever, chest tightness, and fatigue. She was diagnosed with COVID-19 infection confirmed by real-time reverse-transcriptase-polymerase chain reaction. CT showed rapidly progressing peripheral consolidations and ground-glass opacities in both lungs. After treatment, the lesions were shown to be almost absorbed leaving the fibrous lesions.

Association between COVID-19 incidence and outcome and national development levels: An ecologic analysis

This study aimed to evaluate the association between COVID-19 incidence and outcome and national development level. Spearman correlation analysis method was performed to analyze the relationship between COVID- 19 incidence, mortality, and recovery rates as of 27 August 2020 and Human Development Index (HDI) and Inequalityadjusted Human Development Index (IHDI) from 177 countries. The pandemic situation varied obviously from country to country, and the most cases mainly concentrated in few countries with very high or high HDI, such as United States and Brazil. The incidence rates of COVID-19 were significantly positively correlated with HDI and IHDI, but the correlation among mortality, recovery rates, HDI, and IHDI were not significant. In the stratified analysis, the incidence rate in countries with low IHDI and the recovery rate in countries with medium IHDI were significantly positively correlated with IHDI. In countries with very high HDI, the mortality rate was significantly positively correlated with HDI. The findings provide new insights into the relationship between COVID-19 and social determinants of health and inspire policy makers to adjust prevention and control strategies for reducing damages caused by this epidemic. Nevertheless, long-term observation and follow-up studies are necessary to be implemented continuously in the future. [ABSTRACT FROM AUTHOR] Copyright of Science Asia is the property of Science Asia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT?

PURPOSE: To evaluate the diagnostic value of computed tomography (CT) and real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) for COVID-19 pneumonia. METHODS: This retrospective study included all patients with COVID-19 pneumonia suspicion, who were examined by both CT and rRT-PCR at initial presentation. The sensitivities of both tests were then compared. For patients with a final confirmed diagnosis, clinical and laboratory data, in addition to CT imaging findings were evaluated. RESULTS: A total of 36 patients were finally diagnosed with COVID-19 pneumonia. Thirty-five patients had abnormal CT findings at presentation, whereas one patient had a normal CT. Using rRT-PCR, 30 patients were tested positive, with 6 cases initially missed. Amongst these 6 patients, 3 became positive in the second rRT-PCR assay(after 2 days, 2 days and 3 days respectively), and the other 3 became positive only in the third round of rRT-PCR tests(after 5 days, 6 days and 8 days respectively). At presentation, CT sensitivity was therefore 97.2%, whereas the sensitivity of initial rRT-PCR was only 83.3%. CONCLUSION: rRT-PCR may produce initial false negative results. We suggest that patients with typical CT findings but negative rRT-PCR results should be isolated, and rRT-PCR should be repeated to avoid misdiagnosis.